Intrauterine growth retardation in preterm labor and delivery
Gogiia, T.E.; Kintraia, N.P.
Georgian Medical News 129: 30-33
2005
ISSN/ISBN: 1512-0112 PMID: 16444024 Document Number: 586261
We have done retrospective analysis of pregnancy, labor, delivery and neonatal period in 155 women with preterm labor. 78 of them delivered infants with intrauterine growth retardation (IUGR) and 77 women delivered immature infants compared to gestational age. Morphological changes are most prominent in fetal part of placenta, which disturbs blood flow to mother-fetus-placental unit, which in turn leads to intrauterine growth retardation and poor neonatal outcome -- in 78% of cases hypoxic-ischemic CNS disease, in 53% of cases occurs respiratory distress syndrome, pathological functional state and immature cerebral structures according to EEG. Based on case-control study it was documented, that preterm birth is one of the risk factors of IUGR, Odds Ratio is equal to 1.22. Preterm birth of any origin occurs in association with placental insufficiency.