Plasma cell leukaemia
Rodriguez, C.; Pont, J.-C.; Gouin-Thibault, I.; Andrieu, A.-G.; Molina, T.; Le Tourneau, A.; Le Garff-Tavernier, M.; Siguret, V.; Chaibi, P.
Annales de Biologie Clinique 63(5): 535-539
2005
ISSN/ISBN: 0003-3898 PMID: 16230292 Document Number: 589104
We report a case of primary plasma cell leukaemia, with an absolute count of plasma cells of 53 Giga/L, diagnosed in a 83-year-old woman. The patient's condition improved, with no circulating plasma cells after 3 weeks of treatment, in response to the combination of thalidomide and dexamethasone administered for 5 days followed by thalidomide alone. The clinical presentation, the morphological, flow cytometric and pathophysiological characteristics of the plasma cell leukaemia and the treatment are summarised in this paper.