Anti-ischemic efficacy of combination of trimetazidine with enalapril in patients with stable effort angina and metabolic syndrome

Petelina, T.I.; Gapon, L.I.; Bakhmatova, I.A.; Zhevagina, I.A.; Kalinina, V.A.; Todosiĭchuk, V.V.; Kuznetsov, V.A.; Petelina, T.I; Gapon, L.I; Bakhmatova, I.A; Zhevagina, I.A; Kalinina, V.A; Todosiichuk, V.V; Kuznetsov, V.A

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Anti-ischemic efficacy of combination of trimetazidine with enalapril in patients with stable effort angina and metabolic syndrome

Petelina, T.I.; Gapon, L.I.; Bakhmatova, I.A.; Zhevagina, I.A.; Kalinina, V.A.; Todosiĭchuk, V.V.; Kuznetsov, V.A.

Kardiologiia 45(8): 17-22

2005

ISSN/ISBN: 0022-9040

PMID: 16091635

Document Number: 588371

Efficacy of combination of trimetazidine (60 mg/day) and enalapril in patients with stable effort angina and metabolic syndrome was assessed in a randomized placebo controlled study of 64 patients. Anti-ischemic activity of trimetazidine was found to be significant. It was most pronounced in patients with abnormal 24-hour blood pressure index, waist/hip circumference ratio >1.0 at the background of satisfactory clinical and laboratory compensation of type 2 diabetes.