Chronic EBV-infection in children with a high level of anti-H+/K+-ATPhase antibodies in gastric parietal
Tkachenko, E.I.; Novikova, V.P.; Abdul Satar, S.; Aksenov, O.A.; Mikheeva, E.A.; Goncharova, L.B.; Iur'ev, V.V.; Evstratov, I.S.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 4: 78-80; 113
2005
ISSN/ISBN: 1682-8658 PMID: 16255543 Document Number: 586356
We examined 50 children at the age of 4-17 suffering from chronic gastritis. AntiH+/K+-ATPhase antibodies of gastric parietal cells, anti-EBV antibodies IgG EA and IgM VCA were determined with the help of immune-enzyme analysis methods. The first group comprised 28 children with a high level of antiparietal antibodies in the blood serum, and 22 children with a normal level of antiparietal antibodies made up the second group. The HP identification was carried out for all children. Anti-EBV antibodies IgG EA were found in 72% of children, and there were no statistical differences in the frequency and level of antibodies IgG EA. IgM VCA were not found in any of the patients. However, HP-infection was revealed in 64.3% in the first group vs. 22.7% in the second group (p < 0,05); the combination of HB and chronic EBV infection was also more frequent in the first group than in the second group (42.8% and 18.1%, respectively, p < 0,05).