Locally produced bovine bone sponge as a haemostatic agent
Ang, C.Y.; Samsudin, A.R.; Karima, A.M.A.-S.; Nizam, A.
Medical Journal of Malaysia 59 Suppl B: 149-150
2004
ISSN/ISBN: 0300-5283 PMID: 15468862 Document Number: 583319
The aim of this study was to evaluate the morphological and biological properties of a locally produced "Bovine Bone Sponge" for use in dentistry. Bovine bone sponge was prepared from local calf bone. Endotoxin level and surface properties were investigated. The pore size and water uptake ability were measured and results were compared with the commercial haemostatic agent. The material was tested for its haemostatic property and its inhibition of alveolar bone resorption in a sheep model following dental extraction. Results revealed a significant difference in haemostatic effect, and a shorter bleeding time and a lower rate of alveolar bone resorption in bovine bone sponge compare to a commercial haemostatic agent.