Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function mandibular advancement
Li, X.-b.; Chen, K.-y.; Zhou, Z.; Luo, S.-j.
Hua Xi Kou Qiang Yi Xue Za Zhi 22(1): 29-31
2004
ISSN/ISBN: 1000-1182 PMID: 15017694 Document Number: 582314
To investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats. The mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T. T was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05). 1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.