Efficacy of cytoflavin in spondylogenic radiculomyeloischemia
Skoromets, A.A.; Nikitina, V.V.; Bykovitskiĭ, D.M.; Pospelova, M.L.; Sichkar', O.G.; Skoromets, A.P.; Skoromets, T.A.; Solonskiĭ, A.V.; Timofeeva, A.A.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 104(5): 24-27
2004
ISSN/ISBN: 1997-7298 PMID: 15272628 Document Number: 581453
The efficacy of cytoflavin in the treatment of 60 patients (39 women, 21 men, age 32-64 year) with spondylogenic cervical and lumbosacral radiculomyeloischemia due to degenerative dystrophic spinal lesions was studied in a randomized double-blind placebo controlled study according to GCP rules. During 10 days 40 patients recieved intravenous cytoflavin dropper injections once daily; 20 patients (control group) received 5% glucose solution as a placebo. Considerable improvement was observed in 70% patients with radiculomyeloischemia of cervical localization and in 65% - with radiculomyeloischemia of lumbosacral segments. In the control group, positive dynamics of neurologic symptoms was 25-30% lower. Cytoflavin significantly reduced cognitive disturbances, improved reparative processes both in the central and peripheral neurons, and may be recommended in ischemic neuronal spinal lesions.