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Effect of lupeol isolated from Crataeva nurvala Buch.-Ham. stem bark extract against free radical induced nephrotoxicity in rats

Shirwaikar, A.; Setty, M.; Bommu, P.

Indian Journal of Experimental Biology 42(7): 686-690

2004

ISSN/ISBN: 0019-5189
PMID: 15339033
Document Number: 580810
Lupeol, isolated from Crataeva nurvala stem bark in doses 40 and 80 mg/kg body weight, po, for 10 days, decreased the concentration of blood urea nitrogen, creatinine and lipid peroxidation and increased glutathione and catalase activities in cisplatin (5 mg/kg body weight, ip) induced nephrotoxicity in rats. The increased glutathione and catalase activities are indicative of antioxidant properties of lupeol.

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Shifow, A.A.; Naidu, M.U.; Kumar, K.V.; Prayag, A.; Ratnakar, K.S. 2000: Effect of pentoxifylline on cyclosporine-induced nephrotoxicity in rats Indian Journal of Experimental Biology 38(4): 347-352
Timoshin, A.A.; Lakomkin, V.L.; Gubkin, A.A.; Ruuge, E.K. 2003: Effect of coenzyme Q10 on free radical centers in isolated rat myocardium tissue Biofizika 48(4): 717-721
Li, N-sheng.; Xiong, X-ming.; Liu, L-ying. 2003: Protective effects of shenmai injection on DPPH free radical-induced injuries in isolated hearts in rabbits Hunan Yi Ke Da Xue Xue Bao 28(3): 247-250
Mishra, U.S.; Chakraborty, P.; Dasgupta, A.; Dastidar, S.G.; Martins, M.; Amaral, L. 2009: Potent bactericidal action of a flavonoid fraction isolated from the stem bark of Butea frondosa In Vivo 23(1): 29-32
Shetty, S.; Udupa, S.L.; Udupa, A.L.; Vollala, V.R. 2006: Wound healing activities of Bark Extract of Jatropha curcas Linn in albino rats Saudi Medical Journal 27(10): 1473-1476
Caraceni, P.; Van Thiel, D.H.; Borle, A.B. 1995: Dual effect of deferoxamine on free radical formation and reoxygenation injury in isolated hepatocytes American Journal of Physiology 269(1 Pt 1): G132-G137
Chen, S. 1992: Quench effect of metallothionein on free radical signal in post-ischemic reperfusion of isolated rat hearts Zhonghua Yi Xue Za Zhi 72(12): 749
Timoshin, A.A.; Lakomkin, V.L.; Ruuge, E.K. 2000: Effect of ischemic preconditioning on free radical centers of the isolated rat heart during ischemia and early reperfusion Biofizika 45(1): 112-118
Shirwaikar, A.; Malini, S.; Kumari, S.C. 2003: Protective effect of Pongamia pinnata flowers against cisplatin and gentamicin induced nephrotoxicity in rats Indian Journal of Experimental Biology 41(1): 58-62
Thieblot, L.; Berthelay, S.; Berthelay, J. 1971: Preventive and curative action of a bark extract from an African plant, Pygeum africanum, on experimental prostatic adenoma in rats Therapie 26(3): 575-580
Saltykova, V.A.; Ustinova, E.E.; Meerson, F.Z. 1987: Effect of adaptation to hypoxia on the resistance of the isolated atrium to the arrhythmia-inducing action of a promoter of free-radical oxidation Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 5: 19-21
Droy-Lefaix, M.T.; Szabo, M.E.; Doly, M. 1993: Ischaemia and reperfusion-induced injury in rat retina obtained from normotensive and spontaneously hypertensive rats: effects of free radical scavengers International Journal of Tissue Reactions 15(2): 85-91
Kumar, G.; Murugesan, A.G.; Rajasekara Pandian, M. 2006: Effect of Helicteres isora bark extract on blood glucose and hepatic enzymes in experimental diabetes Die Pharmazie 61(4): 353-355
Cullen, J.C.; Flint, M.H.; Leider, J. 1975: The effect of dried mussel extract on an induced polyarthritis in rats New Zealand Medical Journal 81(535): 260-261
Olanlokun, J.O.; Bolaji, O.M.; Agbedahunsi, J.M.; Olorunsogo, O.O. 2012: Therapeutic effects of various solvent fractions of Alstonia boonei (apocynaceae) stem bark on Plasmodium berghei-induced malaria African Journal of Medicine and Medical Sciences 41 Suppl: 27-33
Jainu, M.; Vijai Mohan, K.; Shyamala Devi, C.S. 2006: Gastroprotective effect of Cissus quadrangularis extract in rats with experimentally induced ulcer Indian Journal of Medical Research 123(6): 799-806