Urgent problems of experimental modelling of thermal skin burns
Legeza, V.I.; Khrebtovich, V.N.; Zinov'ev, E.V.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 3: 25-28
2004
ISSN/ISBN: 0031-2991 PMID: 15446417 Document Number: 578861
The review presents a critical analysis of principal benefits and shortcomings of standard experimental models of surface and deep thermal burns of the skin. Comparison of the results of experimental studies must rest on reproduction of identical traumas in series of experiments. It is important to choose animals species, burn model, exposition time and thermal agent depending on the study aim. An algorithm of simple and available methods of reproduction of superficial and deep thermal burns of the skin on a rodent model is described.