Postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and pituitary enlargement in primary hypothyroidism
Kroese, J.M.; Grootendorst, A.F.; Schelfhout, L.J.D.M.
Netherlands Journal of Medicine 62(1): 28-30
2004
ISSN/ISBN: 0300-2977 PMID: 15061231 Document Number: 577128
We report a 36-year-old woman with primary hypothyroidism revealed by postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and suprasellar pituitary enlargement on magnetic resonance imaging (MRI). On thyroid hormone replacement therapy all clinical, biochemical, radiological and endocrine abnormalities disappeared. Hyperplasia of pituitary thyrotrophs and/or lactotrophs seems to be responsible for the pituitary enlargement seen on MRI.