Key events in the cell cycle, their regulation and organization
Omel'ianchuk, L.V.; Trunova, S.A.; Lebedeva, L.I.; Fedorova, S.A.
Genetika 40(3): 293-310
2004
ISSN/ISBN: 0016-6758 PMID: 15125243 Document Number: 576176
The review surveys the studies of molecular genetic mechanisms of the cell cycle control on various eukaryotic models. The major cell cycle phenomena are considered: (1) checkpoints and their role in preserving DNA integrity and fidelity of mitosis, (2) the cell oscillator model, and (3) the role of cyclins in timing of cell division and coordination of mitotic events. The main classes of regulatory proteins involved in the cell cycle are discussed in detail.