Characterization of Yersinia pseudotuberculosis heat stable serovar specific polypeptides with the use of monoclonal antibodies
Fedorova, V.A.; Devdariani, Z.L.; Sameliia, Z.G.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2004(3): 10-15
2004
ISSN/ISBN: 0372-9311 PMID: 15346942 Document Number: 576031
The capacity of Y. pseudotuberculosis to express serovar specific polypeptides with different specificity of antigenic determinants was proved with the use of monoclonal antibodies (McAb). For the first time Y. pseudotuberculosis 0 antigens were found to have heat stable protein components carrying linear epitopes comlementary to serovar specific MaAb and ensuring the serological specificity of the infective agent. The possibility of improving intraspecific classification of Y. pseudotuberculosis and their differentiation from other pathogenic Yersinia on the basis of the capacity of these bacteria for synthesizing species and serovar specific proteins is substantiated.