Extra-amniotic balloon with PGE2 versus extra-ovular Foley catheter with PGF2alpha in mid-trimester pregnancy termination
Liu, H.S.; Chang, Y.K.; Chu, T.Y.; Yu, M.H.; Chen, W.H.
International Journal of Gynaecology and Obstetrics the Official Organ of the International Federation of Gynaecology and Obstetrics 63(1): 51-54
1998
ISSN/ISBN: 0020-7292 PMID: 9849711 Document Number: 576005
Objective: The objective of this study was to compare the efficacy and side effects of two methods of midtrimester labor induction, extra-amniotic balloon with intracervical prostaglandin (PG) E2 (0.5 mg X 2) vs. extra-ovular Foley catheter with intrauterine PGF2alpha (1 mg/h X 6). Methods: A cohort of 32 and 36 cases indicated for mid-trimester termination was enrolled and managed with extra-amniotic balloon and extra-ovular Foley catheter methods, respectively. Outcomes of induction-to-delivery interval, induction failure, and occurrence of side effects were assessed. Results: There were no statistical differences in maternal age, parity, gestational age or fetal birth weight between the two groups. Compared with the extra-ovular Foley catheter with PGF2alpha group, the induction-to-delivery interval was significantly shorter in the extra-amniotic balloon plus PGE2 group. There was no significant difference in side effects and major complications developed in either groups. Conclusions: The extra-amniotic balloon with intracervical PGE2 is more efficient in reducing the induction-to-delivery interval for termination of mid-trimester pregnancies than the extra-ovular Foley catheter with intrauterine PGF2alpha.