Diagnosis and treatment for adrenocortical carcinoma
Iihara, M.; Obara, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 31(3): 342-345
2004
ISSN/ISBN: 0385-0684 PMID: 15045937 Document Number: 574993
Adrenocortical carcinomas frequently hypersecrete multiple adrenocortical steroids and their precursors. CT scan and MRI usually demonstrate necrotic lesions or areas of calcification in this uncommon tumor. Therapy in patients with adrenocortical carcinoma is less satisfactory. Surgical excision is the primary mode of therapy. Up to the present, mitotane (o, p'-DDD) treatment combined with chemotherapy has been the only palliative measure for patients with nonresectable or extensively recurrent tumors.