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Influence of chemotherapy on Th1/Th2 cytokine switching in stomach cancer patients

Li, Y.; Liang, J.; Liu, W.-b.; Xu, X.-q.; Zhao, Y.-r.

Zhonghua Zhong Liu Za Zhi 26(12): 732-734

2004

ISSN/ISBN: 0253-3766
PMID: 15733391
Document Number: 572294
To observe the influence of chemotherapy on the switching of Th1/Th2 cytokines in stomach cancer patients. Th1/Th2 cytokine genes expressed by peripheral blood mononuclear cells of stomach cancer patients before and after chemotherapy were detected by RT-PCR. The expression of Th2 cytokines was dominant in patients before chemotherapy, and the dominancy became less marked after chemotherapy. The immune deviation with Th2 predominance in stomach cancer patients has a tendency to become reversed after chemotherapy.

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