Antithrombotic treatment of acute coronary syndrome
Bergovec, M.
Acta Medica Croatica Casopis Hravatske Akademije Medicinskih Znanosti 58(2): 119-122
2004
ISSN/ISBN: 1330-0164 PMID: 15208796 Document Number: 570549
After we have become aware that arteriosclerosis provokes thrombotic and thromboembolic process, which is the most common cause of occlusion of coronary arteries, in the past 30 years significant improvements have been made in antithrombotic treatment of acute coronary syndrome. Antithrombotic therapy of acute coronary syndrome has been explored in few directions. These are thrombolytic multidrug therapy, anticoagulant therapy with nonfractional and low molecular heparin, therapy with glycoprotein IIb/IIIa receptor antagonists and antiaggregation therapy with acetylsalicylic acid and tienopyrid. Research results and clinical experience point to a conclusion that antithrombotic therapy is the cornerstone in the mariagement of acute coronary syndrome. In this paper, results of major studies and main antithrombotic treatment guidelines in acute coronary syndrome accepted by international professional associations are presented.