Merogony of Toxoplasma gondii (Apicomplexa: Coccidia) and its effect on the mortality and histopathology in the house mouse Mus musculus

Fayed, H.M.; Allam, K.A.M.; Ali, N.-E.S.-E.

Journal of the Egyptian Society of Parasitology 34(1): 45-64

2004


ISSN/ISBN: 1110-0583
PMID: 15125516
Document Number: 569940
Merogonic stages of Toxoplasma gondii, their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses (LD&HD) of T. gondii sporulated oocysts was investigated. The mortality percentage in LD group was 16%, 20%, 28% and 72%, while that in HD group was 36%, 56%, 72% and 100% in the 1st-4th week, respectively. Meanwhile, the maximum mortality percentage of the control group reached 6%. The histopathological changes induced by the parasite in different organs such as kidneys, liver, brain, spleen, heart, lungs and testes were discussed.

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