Cytophagic histiocytic panniculitis: a report of 6 cases with literature review
Li, M-tao.; Zeng, X-feng.; Zhang, F-chun.; Tang, F-lin.
Zhonghua Nei Ke Za Zhi 43(8): 576-579
2004
ISSN/ISBN: 0578-1426 PMID: 15355660 Document Number: 568605
To study the clinical characteristics of cytophagic histiocytic panniculitis (CHP) and increase the understanding of CHP. Clinical data of six cases with CHP in our hospital from 1994 were presented with literature review. (1) Six patients including five females, at a mean age of 21.8 year, suffered from the diseases for a mean period of 12.7 months; (2) The major clinical presentations included fever (6/6), subcutaneous nodules (6/6), splenomegaly (5/6) and hepatomegaly (4/6); The laboratory examinations showed elevated hepatic enzymes (4/6), coagulative dysfunction (2/6) and hemocytopenia (3/6); (3) The pathologic examinations revealed benign histiocytes that infiltrated the adipose tissues (6/6) and hemopieotic tissue (3/3), phagocytosing hemocytes; (4) Only one patient was treated with combined chemotherapy. CHP should be considered based on its unique clinical characteristics and would be diagnosed depending on pathology. The aggressive treatment of combined chemotherapy might improve the prognosis.