Evaluation of CD4 counts and percentages in the HIV infected Indian population

Vajpayee, M.; Kanswal, S.; Wig, N.; Seth, P.

Southeast Asian Journal of Tropical Medicine and Public Health 35(1): 144-146

2004


ISSN/ISBN: 0125-1562
PMID: 15272758
Document Number: 568224
This study was designed to evaluate the absolute CD4+ counts and percentages in HIV subtype C infected patients at a tertiary care hospital in northern India. The CD4+ counts of 377 HIV seropositive subjects were estimated by a FACS Calibur (BD) flow cytometer. Dual color immunophenotyping was performed on each sample, which was acquired and analysed using CellQUEST software. Discordance between CD4+ counts and percentages were found more in the early stage ie Group A (37.2%) when compared with Group B (31.6%) and Group C (28.8%), with the counts remaining in the normal range but percentages being severely depressed.

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