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Guided reconstruction of soft tissue defects of the palate with n-HA/PA66 plates: an experimental study in goats

Luo, E.; Yu, L.; Zheng, Q.; Wei, S.-c.; Wang, H.-z.; Li, Y.-b.; Wei, J.; Zuo, Y.

Shanghai Kou Qiang Yi Xue 13(5): 389-392

2004

ISSN/ISBN: 1006-7248
PMID: 15514863
Document Number: 568146
To evaluate the effect of n-HA/PA66 plate as a guided implant for the regeneration of the soft tissue defects in palatal region of goats. 12 goats were divided into experimental group and control group at random. 18.0 mm x 14.0 mm soft tissue defect and 15.0 mm x 13.0 mm hard tissue defect were formed artificially in hard palate. n-HA/PA66 plates were implanted to the defect in the experimental group. The tissue regeneration in the defects was observed and the structure of regenerating tissue was analyzed by histology. The mucoperiosteal tissue in the experimental group regenerated along the n-HA/PA66 plates and the mucoperiosteal defects were closed in 6 weeks. The soft and hard tissues were not closed up in control group in 6 weeks. n-HA/PA66 plates can guide the regeneration of mucoperiosteal tissue to close the palatal defects.

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