Differential clinical diagnostic parameters of acute hepatitis B and flare of chronic HBV infection
Zhao, H.; Tian, G.-s.
Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 18(4): 363-365
2004
ISSN/ISBN: 1003-9279 PMID: 15650791 Document Number: 567366
To evaluate useful clinical diagnostic parameters for differentiating acute hepatitis B and flare of chronic HBV infection. Using PCR method to detect viral level in the patient's serum, HBV marker was detected by ELISA kit. Liver function was also detected. The patient can be diagnosed as acute hepatitis B if a patient has one of the following parameters: (1)HBV-DNA negative on admission. (2) When the patient's ALT was lower than 400 IU/L, HBV-DNA was negative or HBsAg became negative or HBeAg/HBeAb seroconverted. The viral DNA level, HBV marker and ALT can help differentiate acute hepatitis B and flare of chronic HBV infection.