Proteolytic activity, components of the hemostatic system and protein degradation in cholesteatoma and granuloma of the middle ear in children and adults
Chodynicki, S.; Worowski, K.; Popko, E.
Przeglad Lekarski 41(10): 601-604
1984
ISSN/ISBN: 0033-2240 PMID: 6545703 Document Number: 5669
Activity of A and D cathepsines, tromboplastine, plazminogen activator in cholesteatoma and granuloma taken from children is higher than cholesteatoma and granuloma taken from adults. The amount of soluble proteina, peptides and alfa-amine nitrogen in cholesteatoma and granuloma taken from children is lower then in the analogous tissues of adults. High proteolitic activity and a low amount of protein degradation products such as peptides and alfa-amine nitrogen in cholesteatoma and granuloma is an evidence of the great activity of these pathological tissues in temporal bone destruction occurring especially in children.
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