Methods for the assessment of quality and stability of azidocillin
Płotkowiak, Z.; Popielarz-Brzezińska, M.; Serafin, M.
Acta Poloniae Pharmaceutica 60(2): 112-115
2003
ISSN/ISBN: 0001-6837 PMID: 13678317 Document Number: 566602
UV and VIS spectrophotometric methods, after previous chromatographic separation (TLC/UV) and iodometric methods were adapted for the determination of azidocillin in presence of its breakdown products. These methods were applied for kinetic measurement of changes in the azidocillin concentration with time in water solutions and solid state. Using thin layer chromatography several decomposition products of azidocillin were detected.
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