Progynon, a depot preparation with oestrogenic action, in the treatment of prostatic carcinoma
Birke, G.; Wadström, L.B.
Acta Chirurgica Scandinavica 130(4): 388-392
1965
ISSN/ISBN: 0001-5482 PMID: 5842513 Document Number: 5663
A derivative of a natural oestrogen oestradiol undecylate, Progynon-Depot - was given in depot form by injection to a group of patients with prostatic carcinoma. The study showed ProgynonDepot to reduce the excretion of androgen metabolites in the urine. The results suggest that the preparation reduced the testicular production of androgens but probably not that of the adrenal glands. The depot effect and clinical action of the preparation are described briefly.
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