Abnormal chromatin clumping syndrome during treatment with mycophenolate mofetil
Smadja, D.; Lemaire, P.; Atkhen, N.
Annales de Biologie Clinique 61(4): 463-465
2003
ISSN/ISBN: 0003-3898 PMID: 12915357 Document Number: 565957
We describe an abnormal chromatin clumping phenomenon (ACC) with nuclear loss of segmentation on circulating neutrophils in three patients receiving mycophenolate mofetil (Cellcept). It is worth being aware of this rare adverse event because of its unknown origin and of its possible clinical consequences.
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