Combining cohort analysis and monitoring of HIV early-warning indicators of drug resistance to assess antiretroviral therapy services in Vietnam
Do, T.N.; Nguyen, T.M.T.; Do, M.H.; Masaya, K.; Dang, T.B.; Pham, T.L.; Yoshikawa, K.; Cao, T.T.T.; Nguyen, T.T.V.; Bui, D.D.; Nguyen, V.K.; Nguyen, T.L.; Fujita, M.
Clinical Infectious Diseases An Official Publication of the Infectious Diseases Society of America 54(Suppl 4): S306-S312
2012
ISSN/ISBN: 1537-6591 PMID: 22544193 DOI: 10.1093/cid/cir1045Document Number: 565219
Antiretroviral therapy (ART) retention and 5 early-warning indicators (EWIs) of HIV drug resistance (HIVDR) were abstracted at 27 adult and 4 pediatric clinics in Vietnam in 2009. Of 4531 adults and 313 children, 81.2% and 84.4% respectively were still on ART at 12 months. More than 90% of the clinics monitored achieved the World Health Organization (WHO) targets for lost-to-follow-up (LTFU), ART prescribing practices, and ARV supply continuity. Only 83.9% of the clinics met the target for first-line ART retention and 79.3% met the target for clinic appointment-keeping. Clinic factors (i.e. number of patients, administrative level, and geographical region) were associated with ART retention and LFTU. Data were useful in guiding public health action to optimize ART services.