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Monitoring of early warning indicators for HIV drug resistance in antiretroviral therapy clinics in Zimbabwe

Dzangare, J.; Gonese, E.; Mugurungi, O.; Shamu, T.; Apollo, T.; Bennett, D.E.; Kelley, K.F.; Jordan, M.R.; Chakanyuka, C.; Cham, F.; Banda, R.M.

Clinical Infectious Diseases An Official Publication of the Infectious Diseases Society of America 54(Suppl 4): S313-S316

2012

ISSN/ISBN: 1537-6591
PMID: 22544194
DOI: 10.1093/cid/cir1014
Document Number: 565218
Monitoring human immunodeficiency virus drug resistance (HIVDR) early warning indicators (EWIs) can help national antiretroviral treatment (ART) programs to identify clinic factors associated with HIVDR emergence and provide evidence to support national program and clinic-level adjustments, if necessary. World Health Organization-recommended HIVDR EWIs were monitored in Zimbabwe using routinely available data at selected ART clinics between 2007 and 2009. As Zimbabwe's national ART coverage increases, improved ART information systems are required to strengthen routine national ART monitoring and evaluation and facilitate scale-up of HIVDR EWI monitoring. Attention should be paid to minimizing loss to follow-up, supporting adherence, and ensuring clinic-level drug supply continuity.

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