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The prevalence and clinical relevance of p27 and cyclin E immunoreactivity in myelodysplastic syndromes

Pruneri, G.; Fracchiolla, N.; Cortelezzi, A.; Ponzoni, M.; Maisonneuve, P.; Lambertenghi-Deliliers, G.

Haematologica 88(1): 109-110

2003

ISSN/ISBN: 0390-6078
PMID: 12551833
Document Number: 564461
We report on p27 and cyclin E immunoreactivity (IR) in 86 patients with myelodysplastic syndromes (MDS). No association was found between cyclin E IR and survival in the whole series. Cyclin E IR was more prevalent in patients with refractory anemia (RA) and RA with ringed sideroblasts (RARS) with poor survival, although this trend was not statistically significant.

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