Aspergillus infection after total knee arthroplasty
Langer, P.; Kassim, R.A.; Macari, G.S.; Saleh, K.J.
American Journal of Orthopedics 32(8): 402-404
2003
ISSN/ISBN: 1078-4519 PMID: 12943343 Document Number: 564438
The literature includes little information about the treatment protocol for Aspergillus infection after total knee arthroplasty. In this article, we describe the case of a nonimmunocompromised patient who lacked predisposing risk factors and who initially presented with aseptic loosening of a total knee prosthesis that postoperatively had grown Aspergillus niger. Intraoperative culture and frozen-section results for the pseudocapsule were negative. Two days postoperatively, culture results showed heavy growth of A niger. The patient was treated with a 6-week course of amphotericin B followed by oral antifungal therapy. She was doing well and had no symptoms 12 months after surgery.