Use of LHRH agonists and antagonists in male contraception: a review
Sundaram, K.
Contraception 29(2): 163-170
1984
ISSN/ISBN: 0010-7824 PMID: 6373134 DOI: 10.1016/0010-7824(84)90026-xDocument Number: 562788
Agonists and antagonists of LHRH have been shown to inhibit testicular function in animals and are considered to offer potential for nonsteroidal contraception. In men, they offer one of the few promising approaches to reversible suppression of spermatogenesis. They do, however, also depress testosterone synthesis, thus causing loss of libido, necessitating the administration of supplemental androgens.
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