Determination of IgE in the serum of patients with allergic reactions to four species of fish-parasite anisakids
Valero, A.; Terrados, S.; Díaz, V.; Reguera, V.; Lozano, J.
Journal of Investigational Allergology and Clinical Immunology 13(2): 94-98
2003
ISSN/ISBN: 1018-9068 PMID: 12968392 Document Number: 562092
This study investigates cross-reactions between somatic and metabolic antigens of various anisakids in the serum of patients with allergic processes. Twenty patients with allergic reactions after eating fish were studied using the skin-prick test for sensitivity to four species of anisakids [Spain; date not given]. IgE was also determined by immunoblotting in the serum of these patients when confronted with somatic and metabolic antigens of Anisakis simplex s. 1. and Hysterothylacium aduncum, and somatic antigens of A. physeteris and H. fabri. The results obtained with both techniques were basically similar, the following facts being of particular note: (1) four patients presented specific IgE for A. simplex s. 1. and one for Hysterothylacium sp. only; and (2) eight patients presented cross sensitivity for A. simplex s. 1. and A. physeteris, two for A. simplex s. 1. and Hysterothylacium sp., one for A. physeteris and Hysterothylacium sp., and two for A. simplex s. 1., A. physeteris and Hysterothylacium sp. Given the results obtained, it should be considered that other species of fish-parasite anisakids, apart from A. simplex s. 1., may be involved in the allergic reactions presented by a large number of patients.