Pharmacokinetics of alprazolam
Abernethy, D.R.; Greenblatt, D.J.; Divoll, M.; Shader, R.I.
Journal of Clinical Psychiatry 44(8 Pt 2): 45-47
1983
ISSN/ISBN: 0160-6689 PMID: 6135693 Document Number: 5605
The metabolic profile and human pharmacokinetics of alprazolam, a benzodiazepine of unique chemical structure, are discussed. Alprazolam's pharmacokinetics may be altered by age and sex, body weight, and concurrent treatment with cimetidine. The unique structure of alprazolam may be associated with a wider range of biologic activity than is seen with other benzodiazepines.
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