Benzodiazepine receptor number after acute administration of alprazolam and diazepam
Sethy, V.H.; Harris, D.W.
Research Communications in Chemical Pathology and Pharmacology 35(2): 229-235
1982
ISSN/ISBN: 0034-5164 PMID: 6122240 Document Number: 187327
Acute administration of alprazolam and diazepam (50 mg/kg i.p.) significantly increased benzodiazepine receptors in distilled water-washed rat brain membrane preparation. Similar effects were not observed when rat brain membranes were washed with phosphate-buffered saline. Results are discussed with respect to solubilization of benzodiazepine receptors in distilled water.
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