Immunochemical screening: manipulation, handling and interpretation errors, exemplified by benzodiazepines
Schütz, H.; Verhoff, M.A.; Erdmann, F.; Weiler, G.ün.
Archiv für Kriminologie 212(5-6): 141-150
2003
ISSN/ISBN: 0003-9225 PMID: 14723121 Document Number: 559790
The article describes problems related to immunochemical screening-tests with special regard to benzodiazepines, which are commonly used for therapeutic purposes. Focal points are adulteration, manipulation and handling of samples, the selection of cut-off-values, specificity and cross-reactivity, influence of biotransformation and frequently observed pitfalls in the interpretation of the analytical results.