Inflammation-induced alternations in local and central Met-enkephalin in mice
Chadzinska, M.; Scislowska-Czarnecka, A.; Pierzchala-Koziec, K.; Plytycz, B.
Polish Journal of Pharmacology 55(3): 467-470
2003
ISSN/ISBN: 1230-6002 PMID: 14506328 Document Number: 556570
The local increase in Met-enkephalin level during zymosan-induced peritonitis may be related to its local production by exudatory leukocytes (as evidenced by our previous experiments) and influx from distal centers, as its level is significantly decreased in blood, inguinal lymph nodes, and some brain areas (striatum, hypothalamus, and pituitary gland).
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