Diagnosis and importance of the opportunistic herpes-virus infection in etiology and pathogenesis of different eye diseases
Andzhelov, V.O.; Krichevskaia, G.I.; Katargina, L.A.; Maĭchuk, I.F.; Kazachenko, M.A.; Zvonarev, A.Iu.; Kuliakina, M.N.; Tsutskiridze, N.P.; Khvatova, A.V.; Zaĭtsev, I.Z.
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 2003(5): 21-23
2003
ISSN/ISBN: 0869-6047 PMID: 12800484 Document Number: 556495
A total of 439 patients (adults - 184, children - 255) with herpetic keratitis as well as with uveitis and choriorenitis of different geneses and localizations were examined. An aggravation of HSV-infection was determined by detecting, in the blood), anti-bodies to the unstructured early viral antigens by using the immune enzyme analysis (IEA). The efficiency of the test was demonstrated during the examination of patients with different ophthalmic pathologies. An active infection was detected in 16-39% of patients with various ocular diseases of non-herpetic etiology. The pathogenetic value of reactivated HSV infection is diverse: it can function as an etiological or trigger factor and it can aggravate the main disease through causing, postoperatively, complications.