The importance of interleukin 6 (IL-6) in pathogenesis and diagnosis of renal glomerular diseases
Kacprzyk, F.
Postepy Higieny i Medycyny Doswiadczalnej 49(4): 513-522
1995
ISSN/ISBN: 0032-5449 PMID: 8657645 Document Number: 451244
IL-6 synthesized by various types of cells and has multiple biological functions. In the kidney, IL-6 is synthesized by mesangial cells and acts as an autocrine growth factor. IL-6 was demonstrated in the glomerular mesangium and in the urine of patients with proliferative glomerulonephritis, suggesting that it has an important role in the pathogenesis of renal glomerular diseases.
Document emailed within 1 workday
Related Documents
Brzosko, W.J. 1972: Importance of immunomorphological studies in determination of pathogenesis of renal diseases Przeglad Lekarski 29(11): 909-912Tomura, S.; Tsutani, K.; Sakuma, A.; Takeuchi, J. 1985: Discriminant analysis in renal histological diagnosis of primary glomerular diseases Clinical Nephrology 23(2): 55-62
Andzhelov, V.O.; Krichevskaia, G.I.; Katargina, L.A.; Maĭchuk, I.F.; Kazachenko, M.A.; Zvonarev, A.Iu.; Kuliakina, M.N.; Tsutskiridze, N.P.; Khvatova, A.V.; Zaĭtsev, I.Z. 2003: Diagnosis and importance of the opportunistic herpes-virus infection in etiology and pathogenesis of different eye diseases Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 2003(5): 21-23
Romano, M.; Baio, A. 1984: Importance of ultrasonography in the differential diagnosis of various renal diseases Minerva Urologica e Nefrologica 36(4): 301-305
Waldmann, G.; Henzgen, S. 1983: Morphology and pathogenesis of glomerular renal lesions in gold nephropathy Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 128(1-2): 41-52
Egido, J.; Gómez-Chiarri, M.; Ortíz, A.; Bustos, C.; Alonso, J.; Gómez-Guerrero, C.; Gómez-Garre, D.; López-Armada, M.J.; Plaza, J.; Gonzalez, E. 1993: Role of tumor necrosis factor-alpha in the pathogenesis of glomerular diseases Kidney International. Suppl 39: S59-S64
Naturska-Targosz, H. 1974: Laboratory diagnosis of renal diseases. XIV. Role of renal vessels studies in the diagnosis of renal diseases Przeglad Lekarski 31(9): 815-817
Barillé, S.; Bataille, R.; Amiot, M. 2000: The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma European Cytokine Network 11(4): 546-551
Naskalski, J. 1974: Laboratory diagnosis of renal diseases. 8. Main biochemical determinations used in the diagnosis of renal diseases Przeglad Lekarski 31(6): 629-632
Inage, H.; Koyama, A.; Watanabe, K.; Suzuki, H.; Narita, M.; Tojo, S. 1983: Study of platelet involvement in glomerular renal diseases Nihon Jinzo Gakkai Shi 25(1): 93-104
Kanjanabuch, T.; Kittikovit, W.; Lewsuwan, S.; Leelahavanichkul, A.; Avihingsanon, Y.; Praditpornsilpa, K.; Eiam-Ong, S.; Tungsanga, K.; Sitprija, V. 2005: Etiologies of glomerular diseases in Thailand: a renal biopsy study of 506 cases Journal of the Medical Association of Thailand 88(Suppl 4): S305-S311
Stejskal, J.; Pirani, C.L.; Okada, M.; Mandelanakis, N.; Pollak, V.E. 1973: Discontinuities (gaps) of the glomerular capillary wall and basement membrane in renal diseases Laboratory Investigation; a Journal of Technical Methods and Pathology 28(2): 149-169
Vleming, L.J.; Baelde, J.J.; Westendorp, R.G.; Daha, M.R.; van Es, L.A.; Bruijn, J.A. 1997: The glomerular deposition of PAS positive material correlates with renal function in human kidney diseases Clinical Nephrology 47(3): 158-167
Tuszewska, R.; Gieldanowski, J. 1977: Modern views on the mechanism of immune processes: 2. Importance for the pathogenesis of eyeball diseases Klinika Oczna 47(8): 355-358
Sohtome, S.; Ishitobi, F.; Waku, S.; Mizoguchi, K.; Ueda, Y. 1983: Pathological studies on focal glomerular sclerosis (FGS) in rats--Glomerular changes and distribution in the renal cortex Nihon Jinzo Gakkai Shi 25(4): 363-373
Oite, T.; Yao, J. 2009: Disturbances of glomerular hemodynamics: a risk factor determing progression of glomerular diseases? Journal of Nephrology 22(2): 196-202
Schilling, V.; Negri, B.; Bujía, J.; Schulz, P.; Kastenbauer, E. 1992: Possible role of interleukin 1 alpha and interleukin 1 beta in the pathogenesis of cholesteatoma of the middle ear American Journal of Otology 13(4): 350-355
Woo, J.; Floyd, M.; Cannon, D.C. 1981: Albumin and beta 2-microglobulin radioimmunoassays applied to monitoring of renal-allograft function and in differentiating glomerular and tubular diseases Clinical Chemistry 27(5): 709-713
Turbat-Herrera, E.A.; Isaac, J.; Sanders, P.W.; Truong, L.D.; Herrera, G.A. 1997: Integrated expression of glomerular extracellular matrix proteins and beta 1 integrins in monoclonal light chain-related renal diseases Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology Inc 10(5): 485-495
Ditmar, R.; Steidl, L. 1987: The importance of magnesium in orthopedics. IV. the role of magnesium deficiency in the pathogenesis of osteoarticular diseases Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca 54(5): 385-399