Retinoblastoma in monozygotic twins
Procházková, D.; Konecná, P.; Cíhalová, V.; Hrstková, H.; Rehůrek, J.; Autrata, R.
Ceska a Slovenska Oftalmologie Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti 59(2): 134-140
2003
ISSN/ISBN: 1211-9059 PMID: 12825405 Document Number: 555984
Retinoblastoma is one of the most frequent ophthalmological tumours in children. It is an embryonic tumour originating in the retina. It is caused by abnormalities in the RB1 gene and deletions in the region 13q14. The authors present a bilateral non-hereditary retinoblastoma in monozygotic twins, associated with deletion in the region 13q14, stigmatization, psychomotor and somatic retardation.