Panhypopituitarism in one of 2 monozygotic twins

Boudailliez, B.; Goldfarb, A.; Pautard, J.C.; Lenaerts, C.; Risbourg, B.; Piussan, C.

Archives Francaises de Pediatrie 40(3): 171-173

1983


ISSN/ISBN: 0003-9764
PMID: 6683957
Document Number: 209445
Anterior panhypopituitarism has been observed in one of monozygous twin girls. Etiologic investigations were negative and only suggested an hypothetic perinatal insult. Genetic abnormalities could be excluded. Replacement therapy with human growth hormone was strikingly successful, with a remarkable catch-up growth and, however, a velocity of bone age comparable with the velocity of growth.

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