Tuberculosis and molecular biology
Andersen, A.B.år.; Lillebaek, T.; Søborg, C.; Johansen, I.S.; Thomsen, V.Øs.
Ugeskrift for Laeger 165(9): 920-922
2003
ISSN/ISBN: 0041-5782 PMID: 12661517 Document Number: 555215
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB) hunting millions worldwide, is a challenge to work with in the laboratory. Modern molecular biology has provided extremely useful tools which have changed conventional diagnostic procedures in the TB laboratories. Research in molecular epidemiology is currently expanding our knowledge of the natural history of TB. Access to the genome sequence has opened new avenues for research in drug development and new vaccines. However, we are still awaiting the impact of these efforts in the resource-poor TB endemic countries.