Results of a multicenter study of Rebif-22 mcg administration in Russia
Zavalishin, I.A.; Gusev, E.I.; Iakhno, N.N.; Skoromets, A.A.; Boĭko, A.N.; Demina, T.L.; Burlutskiĭ A P; Beĭn, B.N.; Sholomov, I.I.; Pereserdova, A.V.; Stoĭda, N.I.; Zakharova, M.N.; Adarcheva, L.S.; Niiazbekova, A.S.; Askarova, L.S.; Oleĭnikov, V.G.; Rebrova, O.I.; Shmidt, T.E.; Davydovskaia, M.V.; Totolian, N.A.; Beskhmel'nitsina, I.A.; Bragina, O.V.; Ponomareva, G.L.; Durseneva, O.M.; Voronchikhina, S.A.; Volkova, L.I.; Turova, E.L.; Streknev, A.G.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 2003(Special Issue 2): 73-78
2003
ISSN/ISBN: 1997-7298 PMID: 12938639 Document Number: 555132
The results of multicenter study of Rebif 22 micrograms in Russia have been reported. 167 multiple sclerosis patients have received Rebif 22 micrograms three times a week for 1 year. This study provides evidence for reduction of the relapse rate in patients with relapsing/remitting and secondary progressive multiple sclerosis. The tendency to the decrease of the severity of relapses, less need for steroid use and the decrease of EDSS score in patients with relapsing/remitting multiple sclerosis have been shown. In general Rebif 22 micrograms was tolerated well.