Results of the European multicenter study of radionuclide mammography with Tc-99m-MIBi
Grünwald, F.; Palmedo, H.; Mallmann, P.; Biersack, H.J.
Zentralblatt für Chirurgie 123(Suppl 5): 47-48
1998
ISSN/ISBN: 0044-409X PMID: 10063572 Document Number: 494101
In the European multicenter trial 246 female patients with suspicious mammographic result and/or breast mass were studied. In 253 lesions (195 palpable, 58 non-palpable) 165 malignant and 88 benign results were obtained histologically. All scans were evaluated centrally and institutionally. Central evaluation (per lesion) resulted in a sensitivity of 71% and a specificity of 69%. For palpable lesions, sensitivity was 83% in the central read and 91% in the institutional read. No difference was observed between invasive ductal and invasive lobular carcinoma. X-ray density had no influence on scintigraphic sensitivity. Sensitivity and specificity of mammography were 91% and 42%, respectively.