Pentalogy of Cantrell: first trimester prenatal diagnosis and association with multicistic dysplastic kidney
Pollio, F.; Sica, C.; Pacilio, N.; Maruotti, G.M.; Mazzarelli, L.L.; Cirillo, P.; Votino, C.; Di Francesco, D.
Minerva Ginecologica 55(4): 363-366
2003
ISSN/ISBN: 0026-4784 PMID: 14581862 Document Number: 554881
Pentalogy of Cantrell is a rare congenital anomaly consisting of the following features: 1) midline supraumbilical abdominal wall defects; 2) deficiency of the anterior diaphragm; 3) defects in the diaphragmatic pericardium; 4) defects of the lower sternum; 5) congenital intracardiac defects. We report 3 cases of pentalogy of Cantrell diagnosed respectively at 13, 18 and 24 weeks of gestation. In case 1 Cantrell's pentalogy was diagnosed during the 1(st) trimester. Case 2 revealed the coexistence of cystic hygroma. Case 3 showed an association with dysplastic left kidney and mild pyelectasis of the right kidney. Our results confirm the possibility of an early detection of Cantrell's pentalogy and reveal the possibility of associations with other pathological findings.