Thalidomide: (re) discovery of a not very dear old molecule
Bressoud, Aéric.; Schwab, Béatrice.Zimmerli.
Revue Medicale de la Suisse Romande 123(4): 238-240
2003
ISSN/ISBN: 0035-3655 PMID: 15088555 Document Number: 553753
The angiogenesis is an early event in tumorigenesis. Angiogenesis inhibitors have been developed and are now studied in clinical trials. Angiogenesis research has induced a renewal of thalidomide. Thalidomide inhibits tumoral angiogenesis, allowing a good palliative treatment for hematological malignancies, especially for multiple myeloma and myelodysplastic syndromes.
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