Abnormal SPECT myocardial perfusion imaging during periods of obstructive sleep apnea in morbid obese patients without known heart disease
Orea-Tejeda, A.; Valencia-Flores, M.; Castillo-Martinez, L.; Rebollar-Gonzalez, Vónica.; González-Barranco, J.; Castaño, A.; Asensio, E.; Dorantes-Garcia, J.; Sepulveda-Mendez, Jús.; Oseguera-Moguel, J.; García-Ramos, G.; Cano, A.
Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 55(1): 18-25
2003
ISSN/ISBN: 0034-8376 PMID: 12708159 Document Number: 553260
Fourteen patients from the obesity clinic in Mexico City, Mexico, weighing less than 130 kg underwent myocardial perfusion studies, using single photon emission computed tomography, during nighttime. Coronary angiograms were performed on patients with suspected severe coronary obstruction, based on the nighttime myocardial perfusion studies or pharmacological stress carried out during waking hours. All 14 patients manifested myocardial perfusion defects during sleep, affecting an average of 5.5 segments per patient; however, only 8 presented ischaemic ST segment changes, whereas none demonstrated rhythm or conduction disturbances. The angiographic examination of the 10 patients with the most severe perfusion defects did not reveal significant coronary obstruction, and fewer perfusion defects were detected during daytime scintigraphy.