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Treatment with lepirudin in heparin-induced thrombocytopenia. A case report

Nippert, M.; de Maistre, E.; Rodermann, M.; Vançon, A.C.; Amrein, D.; Brembilla-Perrot, B.; Lecompte, T.; Zannad, F.; Aliot, E.

Archives des Maladies du Coeur et des Vaisseaux 95(12): 1234-1238

2002

ISSN/ISBN: 0003-9683
PMID: 12611047
Document Number: 551714
We report the case of a 71 old woman presenting a bilateral massive pulmonary embolism with intraventricular right thrombus complicating heparin induced thrombocytopenia (HIT) persistent after one month of conventional anticoagulant processing. We underline the effectiveness of lepirudin (Refludan) in the curative processing of pulmonary embolism allowing here to avoid a complex surgical thromboembolectomy. We evoke the place of this molecule in the curative therapeutic strategy of HIT with thrombotic phenomena.

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