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Heparin-induced thrombocytopenia and thrombosis: a case study and clinical overview

Lapka, D.M.; Wild, L.D.; Barbour, L.A.

Oncology Nursing Forum 21(5): 871-876

1994

ISSN/ISBN: 0190-535X
PMID: 7937248
Document Number: 432702
To describe the mechanisms and nursing care associated with heparin-induced thrombocytopenia and thrombosis (HITT). Published books and journal articles as well as clinical experience. HITT is an immune reaction that occurs in 1%-10% of individuals receiving heparin therapy. Characterized by a sudden drop in platelets, it can result in life-threatening hemorrhage and thrombus-related events. Heparin commonly is used in many oncology treatment settings. Awareness of this potentially serious complication and knowledge of its treatment is critical to safe administration. Astute assessment skills are the key to diagnosis and treatment of HITT.

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