Osmotic myelinolysis in a normonatremic patient
Kilinç, M.ün.; Benli, U.ü S.; Can, U.
Acta Neurologica Belgica 102(2): 87-89
2002
ISSN/ISBN: 0300-9009 PMID: 12161906 Document Number: 550039
Osmotic demyelination syndrome is usually associated with hyponatremia or rapid correction of this condition. The prognosis is usually fatal. We treated a 34-year-old chronic renal failure patient who did not have hyponatremia but developed severe pontine myelinolysis demonstrated with MRI. Serial MRI revealed gradual reduction of the lesions over 2 months. This case demonstrates that osmotic demyelination syndrome is not always associated with hyponatremia, and that, although the prognosis is usually poor, some patients recover.