A case of liver metastasis from anorectal malignant melanoma treated by chemoembolization
Izawa, H.; Souma, I.; Fukuchi, N.; Yoshida, T.; Ebisui, C.; Sakita, I.; Kanai, T.; Fujimoto, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 29(12): 2350-2353
2002
ISSN/ISBN: 0385-0684 PMID: 12484072 Document Number: 548342
Anorectal malignant melanoma is relatively rare and its prognosis is very poor because of distant metastasis via the blood or lymphatic vessels. This paper reports a case of liver metastasis from anorectal malignant melanoma treated by chemoembolization. A 68-year-old man was admitted to our hospital because abdominal enhanced computed tomography revealed multiple liver metastases. Angiography also revealed metastasis, so a chemoembolization with nedaplatin was performed. Two months later some lesions fell into necrosis but new ones appeared, and the same treatment was performed another three times. Accessory vessels from the inferior diaphragma artery developed and prevented these treatments. The patient died from the progress of metastases to the liver, bone and skin three years and two months after the operation, or one year and three months after the liver recurrence. The chemoembolization showed some effects on liver metastases from malignant melanoma, but they were temporary.