Primary nasal melanoma with exclusive liver metastasis: a case report
Chiou, T.J.; Chen, L.S.; Lin, S.L.; Chen, P.M.
Zhonghua Yi Xue Za Zhi 52(3): 203-206
1993
ISSN/ISBN: 0578-1337 PMID: 8252464 Document Number: 406503
A 50-year-old male presented with a nasal mass causing obstruction and bleeding. The initial biopsy indicated a malignant lymphoma but the subsequent biopsy diagnosed an undifferentiated carcinoma. However, histopathological study and immunohistochemical study, made a final diagnosis of nasal melanoma. Six months after the diagnosis, the patient developed exclusive liver metastasis. He responded to 1 course of intensive chemotherapy with 200 mg/m2 cisplatin and 5000 mg/m2 dacarbazine for 6 months. For patients with nasal cavity malignancy, the possibility of primary melanoma should be considered. Combination chemotherapy with intensive dose of cisplatin and dacarbazine may be a viable treatment regimen for nasal melanoma with liver metastasis.